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Cortrosyn Injection 0.25mg SDV 1mL
$139.95
- Medex SKU:
- APH-00548590000
- Packing Info:
- 1/Each
- Usually Ships:
- 3 - 5 Business Days
- Notice:
- Due to regulatory requirements, this item can only be shipped to customers who have a valid Medical license on file. To add your license information, please click here
Description
Key Features
Active Ingredient: Cortrosyn contains cosyntropin, which is a synthetic form of adrenocorticotropic hormone (ACTH).
Formulation: It comes as a sterile, lyophilized powder in single-dose vials, typically containing 0.25 mg of cosyntropin and 10 mg of mannitol. It needs to be reconstituted with 1 mL of 0.9% Sodium Chloride Injection, USP, right before use.
Administration: It can be given either intravenously (IV) or intramuscularly (IM).
Rapid Action: Cortrosyn quickly triggers a plasma cortisol response, allowing for a fast (e.g., 30-minute) assessment of adrenal function.
Reliable: This medication has been a trusted tool for ACTH Stimulation testing for many years.
Convenient: The test often only requires two blood draws—one before and one after administration.
Flexible: It's suitable for various settings, including office-based or outpatient procedures.
Less Antigenic: Compared to natural ACTH, synthetic cosyntropin has significantly less immunologic activity, which lowers the risk of allergic reactions for most patients, even those who've had hypersensitivity to natural ACTH in the past.
Preservative-Free: As a single-dose injection, it doesn't contain any antimicrobial preservatives.
Uses
Amphastar 00548590000 (Cortrosyn) is primarily used as a diagnostic agent for the ACTH Stimulation Test. This test is vital for:
Screening for Adrenocortical Insufficiency: It assesses the adrenal cortex's ability to respond to ACTH by producing cortisol appropriately. This helps determine if the adrenal and pituitary glands are functioning as they should.
Diagnosing Adrenal Gland Disorders: It's most commonly used when conditions such as:
Addison's disease (primary adrenal insufficiency): Where the adrenal glands themselves aren't making enough cortisol, even if ACTH levels are high.
Pituitary insufficiency (secondary adrenal insufficiency): Where the pituitary gland isn't producing enough ACTH, leading to the understimulation of the adrenal glands.
Differentiating between primary and secondary adrenal insufficiency: The response to Cortrosyn can help tell whether the problem lies with the adrenal glands or the pituitary gland.