- MFR:
- 50-230-71
- Medex SKU:
- FSC-50-230-71
- Packing Info:
- 1/Each
- Usually Ships:
- 1 - 2 Business Days
- Freight Quote Button:
- False
Description
Features of the Reagent Proteins Haptoglobin Human:
- Haptoglobin is a glycoprotein which is synthesized in the liver and circulates in the blood.
- Haptoglobin is produced typically by hepatocytes but also by other tissues: e.g. skin, lung, and kidney.
- It is a positive acute phase protein that binds free hemoglobin and removes it from the circulation to prevent kidney injury, and iron loss following hemolysis.
- The haptoglobin-hemoglobin complex is subsequently removed by the reticuloendothelial system (generally the spleen). As the reticuloendothelial system removes the haptoglobin-hemoglobin complex from the body, haptoglobin levels are reduced in hemolytic anaemias.
- In the course of binding hemoglobin, haptoglobin sequesters the iron inside hemoglobin, preventing iron-utilizing bacteria from benefitting from hemolysis.