Nalbuphine HCl, Preservative Free 10 mg / mL Injection 1 mL 10/Box

$102.95

Description

Active Ingredient: Nalbuphine hydrochloride (10 mg/mL).
Drug Class: Opioid agonist-antagonist analgesic. This means it acts as an agonist at kappa opioid receptors and an antagonist at mu opioid receptors.
Dosage Form: Sterile, nonpyrogenic solution for injection.
Administration: It can be administered by subcutaneous, intramuscular, or intravenous injection.
Onset of Action: Onset of action is typically within 2-3 minutes after intravenous administration and less than 15 minutes after subcutaneous or intramuscular injection.
Duration of Action: The duration of analgesic activity has been reported to range from 3 to 6 hours.
Pain Relief Potency: Its analgesic potency is essentially equivalent to that of morphine on a milligram basis up to a dosage of approximately 30 mg.
Opioid Antagonist Activity: It has opioid antagonist activity, which means it can partially reverse or block opioid-induced respiratory depression from mu-agonist opioid analgesics (like morphine). However, it can also precipitate withdrawal in patients dependent on opioid drugs.
Respiratory Depression Ceiling Effect: Unlike some other opioids, nalbuphine exhibits a ceiling effect for respiratory depression, meaning that doses greater than 30 mg do not produce further respiratory depression in the absence of other CNS depressants affecting respiration.
Preservative-Free: This specific formulation is preservative-free.

Pfizer 00409146301 (Nalbuphine Hydrochloride Injection) is indicated for:

Management of pain: It is used for the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate.
Supplement to balanced anesthesia: It can be used as part of a balanced anesthesia regimen.
Preoperative and postoperative analgesia: Used for pain relief before and after surgical procedures.
Obstetrical analgesia: It can be used for pain relief during labor and delivery.

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