Sodium Bicarbonate 8.4% Injection SDV 8.4% 50mL

$51.95

Description

Active Ingredient: Sodium Bicarbonate ( $NaHCO_{3}$ ): A potent alkalizing agent that dissociates into sodium ( $Na^{+}$ ) and bicarbonate ( $HCO_{3}^{-}$ ) ions in the body.
Concentration: 8.4%, which translates to 1 mEq (milliequivalent) of sodium bicarbonate per milliliter (1 mEq/mL). This is a highly concentrated solution, delivering 50 mEq of sodium bicarbonate in a 50 mL vial.
Volume: 50 mL per single-dose glass flip-top vial. This larger volume is suitable for situations requiring rapid and significant bicarbonate administration.
Preservative Free: This formulation does not contain any preservatives, which is crucial for intravenous administration and prevents potential adverse reactions associated with preservatives.
Sterile and Nonpyrogenic: Ensures the solution is free from microorganisms and fever-producing substances.
Hypertonic Solution: Its high concentration of solutes makes it hypertonic, meaning it has a higher osmolarity than human blood (approximately 2000 mOsmol/L). This property is important to consider during administration, as rapid infusion can lead to fluid shifts.
pH: The solution generally has an approximate pH of 8.0 (ranging from 7.0 to 8.5).
Single-Dose Vial: Designed for single use; any unused portion must be discarded to maintain sterility.

Treatment of Metabolic Acidosis: Its primary indication is for the treatment of metabolic acidosis, which can arise from various severe conditions, including:
- Severe renal disease (kidney failure)
- Uncontrolled diabetes (diabetic ketoacidosis)
- Circulatory insufficiency due to shock or severe dehydration
- Extracorporeal circulation of blood (e.g., during cardiopulmonary bypass)
- Cardiac arrest
- Severe primary lactic acidosis
- Severe diarrhea (which can lead to significant bicarbonate loss)
Certain Drug Intoxications: Used in the treatment of specific drug intoxications, such as:
- Barbiturate poisoning (to promote dissociation of the barbiturate-protein complex)
- Salicylate (aspirin) poisoning
- Methyl alcohol poisoning
Alkalinization of Urine: In hemolytic reactions, it can be used to alkalinize the urine to diminish the nephrotoxicity (kidney damage) of certain substances.
Cardiac Arrest Management: A key component in advanced cardiac life support (ACLS) protocols for managing severe acidosis during cardiac arrest, although its use is specific and guided by blood gas analysis.
Adjunctive Therapy: Used as an adjunct to other therapies to restore acid-base balance and support physiological functions during critical illness.

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